Building a web application using Python typically involves selecting a web framework such as Django, creating a project structure, and designing the database using Django's ORM. Developers define views to handle HTTP requests, create templates for HTML presentation, and establish URL patterns for routing. Form handling, authentication, and authorization are implemented, and static files enhance the user interface. Testing ensures the application's reliability, and deployment involves configuring web and database servers. Continuous integration, continuous deployment, monitoring, and debugging are essential aspects of the development process. Overall, the choice of framework, be it Django, Flask, or others, guides the specific steps in constructing a functional and deployable Python-based web application.